BiochemistrybioRxivPreprint
Computational design of allosteric pathways reprograms ligand-selective GPCR signaling
Mahdi Hijazi, Dániel Kéri, Aurélien Oggier…·P. Barth
This study designs GPCR variants with reprogrammed ligand-selective signaling using computational methods, showing sequence variations impact ligand potency and efficacy.
2 citations