Author

F.P. de Isidro-Gómez

Astex Pharmaceuticals, Cambridge, United Kingdom;ORCID 0000-0003-2289-2364Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Biophysics· 1 Molecular Biology· 1

Signature Assays, Organisms & Methods

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Approach:statistical model· 2 Research Focus:benchmarking· 1 Assay:cryo-EM· 1 Research Focus:drug response / drug discovery· 1

Frequent Co-Authors

Carlos Óscar S. SorzanoiD· 2 shared Jose-Maria CarazoiD· 2 shared Cédric MessaoudiiD· 1 shared David HerrerosiD· 1 shared Estrella Fernández-Giménez· 1 shared Michael SauriD· 1 shared Sergio MarcoiD· 1 shared

Activity by Year

2020-2026 · peak 1/yr

Co-Author Collaboration Network

7 top collaborators · 17 mutual co-author links

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2 shared papersBiophysics

Carlos Óscar S. SorzanoORCID

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2 papers

Recent·Most cited

BiophysicsbioRxivPreprintNov 4, 2026

Facilitating the identification of cryo-EM hit matter in drug discovery with Astex-Faro

Federico P. de Isidro-Gomez, Carlos Oscar S Sorzano, Jose-Maria Carazo, Michael Saur

Astex-Faro improves cryo-EM hit identification by detecting structural deviations and enhancing weak features across diverse datasets.

DOI 10.64898/2026.11.03.763890

cryo-EMstatistical model

𝕏 PostBluesky

Molecular BiologyJournal of Structural Biology XPeer-reviewedJan 1, 2020

Improvements on marker-free images alignment for electron tomography

Carlos Óscar S. Sorzano, F.P. de Isidro-Gómez, Estrella Fernández-Giménez…·Cédric Messaoudi

The paper improves a marker-free image alignment method for electron tomography to enhance 3D reconstruction quality by addressing deformations during acquisition.

16 citations

statistical model

𝕏 PostBluesky