Author

Michael Saur

Astex PharmaceuticalsORCID 0000-0002-6612-6656Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Bioinformatics· 1 Biophysics· 1

Signature Assays, Organisms & Methods

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Research Focus:benchmarking· 2 Research Focus:drug response / drug discovery· 2 Assay:cryo-EM· 1 Research Focus:database / resource· 1 Approach:deep learning· 1 Assay:electronic health records· 1 Research Focus:software / tool· 1 Approach:statistical model· 1

Frequent Co-Authors

Alex BerndtiD· 1 shared Amir Apelbaum· 1 shared Carl R. PoelkingiD· 1 shared Carlos Oscar S SorzanoiD· 1 shared Charlotte Mary DeaneiD· 1 shared Federico P. de Isidro-GomeziD· 1 shared Jose-Maria CarazoiD· 1 shared Judith Reeks· 1 shared

Activity by Year

2025-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

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1 shared paperBioinformatics

Alex BerndtORCID

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2 papers

Recent·Most cited

BiophysicsbioRxivPreprintNov 4, 2026

Facilitating the identification of cryo-EM hit matter in drug discovery with Astex-Faro

Federico P. de Isidro-Gomez, Carlos Oscar S Sorzano, Jose-Maria Carazo, Michael Saur

Astex-Faro improves cryo-EM hit identification by detecting structural deviations and enhancing weak features across diverse datasets.

DOI 10.64898/2026.11.03.763890

cryo-EMstatistical model

𝕏 PostBluesky

BioinformaticsbioRxivPreprintMar 4, 2025

Supervised Deep Learning for Efficient Cryo-EM Image Alignment in Drug Discovery with cryoPARES

Rubén Sánchez-García, Alex Berndt, Amir Apelbaum…·Michael Saur

The paper introduces cryoPARES, a deep learning method for efficient cryo-EM image alignment, enabling faster and automated structure determination with reduced manual intervention.

DOI 10.1101/2025.03.04.641536

electronic health recordsdeep learning

𝕏 PostBluesky