Author

Yvonne Richaud‐Patín

Institut d'Investigació Biomédica de BellvitgeORCID 0000-0003-2293-4691Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cell Biology· 1 Neuroscience· 1

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 2 Research Focus:cell type annotation· 2 Research Focus:differential expression· 2 Research Focus:drug response / drug discovery· 2 Organism:human· 2 Research Focus:cell-cell communication· 1 Approach:experimental assay· 1 Assay:imaging· 1

Frequent Co-Authors

Ángel RayaiD· 2 shared Antonella ConsiglioiD· 2 shared Irene Fernández‐CarasaiD· 2 shared Lucas Blasco-AgelliD· 2 shared Manel JuaniD· 2 shared Meritxell Pons‐EspinaliD· 2 shared Valentina BaruffiiD· 2 shared Alícia GarridoiD· 1 shared

Activity by Year

2024-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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2 shared papersCell Biology

Ángel RayaORCID

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2 papers

Recent·Most cited

Cell BiologyCommunications BiologyPeer-reviewedAug 12, 2025

✦ In-depth digest

LRRK2-mutant microglia and neuromelanin synergize to drive dopaminergic neurodegeneration in an iPSC-based Parkinson's disease model

Lucas Blasco-Agell, Meritxell Pons‐Espinal, Veronica Testa…·Antonella Consiglio

LRRK2 G2019S iPSC-derived microglia exposed to neuromelanin, but not α-synuclein fibrils, reduce healthy dopaminergic neuron numbers in co-culture; ivermectin prevents this, and post-mortem midbrain supports it.

16 citationstop 1%

humanimaging

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NeuroscienceJCI InsightPeer-reviewedFeb 8, 2024

Immunosuppressive tocilizumab prevents astrocyte induced neurotoxicity in hiPSC-LRRK2 Parkinson's disease by targeting receptor interleukin-6

Meritxell Pons‐Espinal, Lucas Blasco-Agell, Irene Fernández‐Carasa…·Antonella Consiglio

The paper shows that tocilizumab, an IL-6 receptor inhibitor, prevents astrocyte-induced neurotoxicity in Parkinson's disease by blocking IL-6 signaling in neurons.

62 citationstop 1%

humanbulk RNA-seq

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