Molecular BiologybioRxivPreprint
The role of aneuploidy and polyclonality in the adaptation of the Protozoan parasite Leishmania to high drug pressure
Gabriel H. Negreira, Robin de Groote, Dorien Van Giel…·Malgorzata A. Domagalska
This study investigates how aneuploidy and polyclonality contribute to Leishmania's adaptation to high drug pressure, showing different dynamics depending on the drug and pre-existing mutations.
DOI 10.1101/2022.12.22.521483