Author

Jorge Castanheira

Centre National de la Recherche ScientifiqueORCID 0000-0003-2307-7206Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Neuroscience· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:human· 1 Organism:mouse· 1

Frequent Co-Authors

Adam GorlewicziD· 1 shared Ana Moreira-de-SáiD· 1 shared Christophe MulleiD· 1 shared Cláudia Guimas AlmeidaiD· 1 shared Farzaneh Sadat MirfakhariD· 1 shared Gaël BarthetiD· 1 shared Jose Silva RamalhoiD· 1 shared Pei ZhangiD· 1 shared

Activity by Year

2022-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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1 shared paperNeuroscience

Adam GorlewiczORCID

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2 papers

Recent·Most cited

NeurosciencebioRxivPreprintAug 31, 2023

The Alzheimer's disease risk gene CD2AP functions in dendritic spines by remodelling F-actin

Farzaneh Sadat Mirfakhar, Jorge Castanheira, Raquel Domingues…·Cláudia Guimas Almeida

This study shows CD2AP regulates dendritic spine morphology and synapse formation by modulating F-actin dynamics, linking its risk variants to Alzheimer's disease synaptic dysfunction.

DOI 10.1101/2023.08.31.555707

humanexperimental assay

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NeuroscienceJournal of NeurosciencePeer-reviewedOct 26, 2022

Presenilin and APP regulate synaptic kainate receptors

Gaël Barthet, Ana Moreira-de-Sá, Pei Zhang…·Christophe Mulle

The paper investigates the role of presenilin and APP in regulating synaptic kainate receptors in Alzheimer's disease models.

14 citations

mouseexperimental assay

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