Author

Xinjia Ruan

China Pharmaceutical UniversityORCID 0000-0003-2309-2641Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Bioinformatics· 1 Immunology· 1

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 2 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Approach:experimental assay· 1 Research Focus:gene regulatory network inference· 1 Organism:human· 1 Approach:machine learning (classical)· 1 Organism:mouse· 1

Frequent Co-Authors

Dian J. CaoiD· 1 shared Fangrong YaniD· 1 shared Guo CheniD· 1 shared Haitao WangiD· 1 shared Hangyu Yan· 1 shared Jialin MengiD· 1 shared Jian‐Guo ZhouiD· 1 shared Jiankun ZhuiD· 1 shared

Activity by Year

2023-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

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1 shared paperImmunology

Dian J. CaoORCID

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2 papers

Recent·Most cited

ImmunologyBasic Research in CardiologyPeer-reviewedMay 7, 2025

The cGAS-STING Pathway Is Essential in Acute Ischemia-Induced Neutropoiesis and Neutrophil Priming in the Bone Marrow

Jiankun Zhu, Xinjia Ruan, MariaSanta C. Mangione…·Dian J. Cao

This study shows that the cGAS-STING pathway is essential for neutrophil production and function in the bone marrow during acute myocardial ischemia, promoting myocardial repair.

13 citationstop 5%

mousebulk RNA-seq

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BioinformaticsThe Innovation MedicinePeer-reviewedJan 1, 2023

DNA replication stress stratifies prognosis and enables exploitable therapeutic vulnerabilities of HBV-associated hepatocellular carcinoma: an in silico strategy towards precision oncology

Xiaofan Lu, Jialin Meng, Haitao Wang…·Fangrong Yan

The paper develops a DNA replication stress-related prognostic index for HBV-associated HCC using machine learning, identifying therapeutic targets and agents for high-risk patients.

5 citations

humanbulk RNA-seq

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