Author

MariaSanta C. Mangione

The University of Texas Southwestern Medical CenterORCID 0000-0003-3894-3533Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

Click to filter author papers

Immunology· 2

Signature Assays, Organisms & Methods

Click to filter · or open tag

Assay:bulk RNA-seq· 2 Research Focus:cell type annotation· 2 Research Focus:differential expression· 2 Approach:experimental assay· 2 Organism:mouse· 2 Research Focus:gene regulatory network inference· 1 Approach:genetic perturbation / CRISPR· 1 Research Focus:host-pathogen & immune response· 1

Frequent Co-Authors

Dian J. CaoiD· 2 shared Pablo Parra· 2 shared Xiang LuoiD· 2 shared Guo Chen· 1 shared Guo CheniD· 1 shared Jiankun ZhuiD· 1 shared Jinhua Wen· 1 shared Xiaoping SuiD· 1 shared

Activity by Year

2025-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 33 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

2 shared papersImmunology

Dian J. CaoORCID

Mutual co-authors in cluster

Author profile →

2 papers

Recent·Most cited

ImmunologybioRxivPreprintMar 10, 2026

Macrophage SLC9A1 Links Endocytic Trafficking to Innate Immune Activation in Myocardial Injury

Jinhua Wen, Pablo Parra, Yoshiharu Muto…·Dian J. Cao

This study identifies SLC9A1 as a mediator linking macrophage endocytic trafficking to innate immune activation in myocardial injury, showing its role in inflammation and cardiac remodeling.

DOI 10.64898/2026.02.27.708643

mousebulk RNA-seq

𝕏 PostBluesky

ImmunologyBasic Research in CardiologyPeer-reviewedMay 7, 2025

The cGAS-STING Pathway Is Essential in Acute Ischemia-Induced Neutropoiesis and Neutrophil Priming in the Bone Marrow

Jiankun Zhu, Xinjia Ruan, MariaSanta C. Mangione…·Dian J. Cao

This study shows that the cGAS-STING pathway is essential for neutrophil production and function in the bone marrow during acute myocardial ischemia, promoting myocardial repair.

13 citationstop 5%

mousebulk RNA-seq

𝕏 PostBluesky