Pharmacology & ToxicologyJournal of Pharmacological and Toxicological MethodsPeer-reviewed
Inhibition of hERG K channels by verapamil at physiological temperature: Implications for the CiPA Initiative
Ashley A. Johnson, Matthew C. Trudeau
This study evaluates the inhibition of hERG channels by verapamil using CiPA protocols, finding similar IC50 and Hill coefficient values across labs and demonstrating improved success rates with a revised protocol.
10 citations