Author

Shimpei Higo

Nippon Medical SchoolORCID 0000-0003-2329-9300Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Neuroscience· 1 Physiology· 1

Signature Assays, Organisms & Methods

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Approach:statistical model· 2 Research Focus:cell type annotation· 1 Research Focus:clustering· 1 Research Focus:differential expression· 1 Research Focus:gene regulatory network inference· 1 Organism:human· 1 Organism:mouse· 1 Organism:rat· 1

Frequent Co-Authors

Hirotaka IshiiiD· 2 shared Arisa Munetomo· 1 shared Asami Kato· 1 shared Ayako Hiragushi· 1 shared Daisuke HishikawaiD· 1 shared Eri Oguri‐Nakamura· 1 shared Haruko Watanabe‐TakanoiD· 1 shared Hideo Mukai· 1 shared

Activity by Year

2025-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 25 mutual co-author links

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2 shared papersPhysiology

Hirotaka IshiiORCID

Mutual co-authors in cluster

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2 papers

Recent·Most cited

PhysiologybioRxivPreprintSep 3, 2026

Age-associated erosion of organ-specific endothelial programs compromises tissue function and resilience

Haruko Watanabe‐Takano, Tomohiro Ishii, Tomohisa Hayakawa…·Shigetomo Fukuhara

This study identifies age-related erosion of organ-specific endothelial programs and links it to tissue dysfunction across multiple organs.

DOI 10.64898/2026.07.02.735775

𝕏 PostBluesky

NeurosciencebioRxivPreprintAug 17, 2025

Age-related decline of synaptic plasticity is regulated by neuro-androgen and neuro-estrogen in normal aging of hippocampus

Suguru Kawato, Yasushi Hojo, Mari Ogiue‐Ikeda…·Shigeo Horie

The paper shows that age-related decline in hippocampal dendritic spine density in male rats is linked to decreased neuro-androgen levels and partially offset by estrogen.

1 citation

ratstatistical model

𝕏 PostBluesky