Author

Haruko Watanabe‐Takano

National Cerebral and Cardiovascular Center Research InstituteORCID 0000-0002-2986-3702Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Developmental Biology· 2 Physiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:mouse· 2 Research Focus:cell type annotation· 1 Research Focus:clustering· 1 Research Focus:differential expression· 1 Research Focus:gene regulatory network inference· 1 Organism:human· 1 Assay:scRNA-seq· 1

Frequent Co-Authors

Ayano ChibaiD· 2 shared Keisuke SakoiD· 2 shared Naoki MochizukiiD· 2 shared Shigetomo FukuharaiD· 2 shared Akihiro YasodaiD· 1 shared Ayaka Matsuo· 1 shared Daisuke HishikawaiD· 1 shared Eri Oguri‐Nakamura· 1 shared

Activity by Year

2019-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 27 mutual co-author links

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2 shared papersDevelopmental Biology

Ayano ChibaORCID

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3 papers

Recent·Most cited

Age-associated erosion of organ-specific endothelial programs compromises tissue function and resilience

Haruko Watanabe‐Takano, Tomohiro Ishii, Tomohisa Hayakawa, Hitoshi Iuchi, Hitomi Matsuno, Eri Oguri‐Nakamura, Kunihito Arai, Kei Yura, Michiaki Hamada, Daisuke Hishikawa, Shota Toyoshima, Mashito Sakai, Shimpei Higo, Masahiro Morishita, Hirotaka Ishii, , Shigetomo Fukuhara

This study identifies age-related erosion of organ-specific endothelial programs and links it to tissue dysfunction across multiple organs.

bioRxiv · Sep 3, 2026 · PreprintPhysiology

Endothelial-zippering proceeds by sensing heartbeat-driven force through Cadherin-6 during heart-vessel connection in zebrafish

Moe Fukumoto, Haruko Watanabe‐Takano, Hajime Fukui, Ayano Chiba, Keisuke Sako, Hiroyuki Nakajima, Naoki Mochizuki

Developmental Cell · Nov 11, 2025Peer-reviewedDevelopmental Biology

Periosteum-derived Osteocrin regulates bone growth through both endochondral ossification and intramembranous ossification

Haruko Watanabe‐Takano, Hiroki Ochi, Ayano Chiba, Ayaka Matsuo, Yugo Kanai, Shigetomo Fukuhara, Keisuke Sako, Takahiro Miyazaki, Shingo Sato, Naoto Minamino, Shu Takeda, Akihiro Yasoda, Naoki Mochizuki

This study shows that Osteocrin promotes both endochondral and intramembranous ossification in long bone growth by enhancing CNP signaling.

bioRxiv · Jul 9, 2019 · PreprintDevelopmental Biology