Mirna Mihovilovic Skanata

CRASH2p enables real-time 3D motion correction for two-photon imaging in freely moving Drosophila larvae, revealing new neural correlates of behavior.

The paper shows that Tmc channels in Drosophila proprioceptors are required for direction-selective activity, with dendrite curvature triggering mechanosensory responses during locomotion.

This paper develops a two-photon tracking microscope with low-latency feedback to enable high-bandwidth neural activity recordings in freely moving fruit fly larvae.