Author

Necla Koçhan

İzmir University of EconomicsORCID 0000-0003-2355-4826Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Assay:bulk RNA-seq· 3 Research Focus:differential expression· 3 Approach:statistical model· 3 Research Focus:benchmarking· 2 Research Focus:gene regulatory network inference· 2 Research Focus:cell type annotation· 1 Research Focus:clustering· 1 Organism:human· 1

Frequent Co-Authors

G. Yazgı TütüncüiD· 2 shared Göknur GineriD· 2 shared Ahu CepheiD· 1 shared Alparslan DemirayiD· 1 shared Enrico GlaabiD· 1 shared Gökmen ZararsıziD· 1 shared Gordon K. SmythiD· 1 shared Gözde Ertürk ZararsıziD· 1 shared

Activity by Year

2019-2025 · peak 1/yr

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10 top collaborators · 24 mutual co-author links

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2 shared papersBioinformatics

G. Yazgı TütüncüORCID

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3 papers

Recent·Most cited

BioinformaticsbioRxivPreprintDec 25, 2025

Multi-Omics Integration Reveals Lipid Metabolic Reprogramming as a Driver of Cystogenesis in Autosomal Dominant Polycystic Kidney Disease (ADPKD)

Gökmen Zararsız, Leila Kianmehr, Alparslan Demiray…·Enrico Glaab

The paper integrates metabolomic and transcriptomic data from ADPKD patients to identify metabolic reprogramming linked to cystogenesis and disease progression.

1 citation

humanmetabolomics

𝕏 PostBluesky

BioinformaticsExpert Systems with ApplicationsPeer-reviewedNov 2, 2020

A new local covariance matrix estimation for the classification of gene expression profiles in RNA-Seq data

Necla Koçhan, G. Yazgı Tütüncü, Göknur Giner

This paper introduces a local covariance matrix estimation method for RNA-Seq data classification, showing improved performance over traditional methods.

9 citations

bulk RNA-seqstatistical model

𝕏 PostBluesky

BioinformaticsPeerJPeer-reviewedDec 18, 2019

qtQDA: quantile transformed quadratic discriminant analysis for high-dimensional RNA-seq data

Necla Koçhan, G. Yazgı Tütüncü, Gordon K. Smyth…·Göknur Giner

The paper introduces qtQDA, a classification method for RNA-seq data that uses quantile transformation and regularized QDA, showing good performance on real datasets.

8 citations

bulk RNA-seqstatistical model

𝕏 PostBluesky