Author

Polly Y. Yu

Harvard UniversityORCID 0000-0003-2406-8723Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Biophysics· 1 Systems Biology· 1

Signature Assays, Organisms & Methods

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Approach:statistical model· 2 Research Focus:cell-cell communication· 1 Assay:fluorescence / live-cell microscopy· 1

Frequent Co-Authors

Arvind SrinivasaniD· 1 shared Benjamin NordickiD· 1 shared Guangyuan Liao· 1 shared Jeremy B. ConwayiD· 1 shared Maxim B. PrigozhiniD· 1 shared Sohaib Abdul RehmaniD· 1 shared Surabhi Kottigegollahalli SreenivasiD· 1 shared Tian HongiD· 1 shared

Activity by Year

2022-2025 · peak 1/yr

Co-Author Collaboration Network

9 top collaborators · 18 mutual co-author links

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1 shared paperBiophysics

Arvind SrinivasanORCID

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2 papers

Recent·Most cited

BiophysicsProceedings of the National Academy of SciencesPeer-reviewedMay 12, 2025

Identifying Intermolecular Interactions in Single-Molecule Localization Microscopy

Xingchi Yan, Polly Y. Yu, Arvind Srinivasan…·Maxim B. Prigozhin

This paper develops a probabilistic algorithm to accurately identify and quantify intermolecular interactions using single-molecule localization microscopy.

5 citations

fluorescence / live-cell microscopystatistical model

𝕏 PostBluesky

Systems BiologyNucleic Acids ResearchPeer-reviewedMar 21, 2022

Nonmodular oscillator and switch based on RNA decay drive regeneration of multimodal gene expression

Benjamin Nordick, Polly Y. Yu, Guangyuan Liao, Tian Hong

The paper shows that regulated RNA degradation can generate oscillations and restore multimodal gene expression in progenitor cells without requiring feedback loops.

33 citations

statistical model

𝕏 PostBluesky