Author

Melanie N. Mendel

Utrecht UniversityORCID 0000-0003-2409-7479Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Research Focus:gene regulatory network inference· 2 Approach:statistical model· 2 Assay:whole-genome sequencing· 2 Research Focus:benchmarking· 1 Research Focus:database / resource· 1 Approach:experimental assay· 1 Research Focus:host-pathogen & immune response· 1 Organism:plant (other)· 1

Frequent Co-Authors

Guido F. J. M. Van den AckervekeniD· 3 shared Joyce Elberse· 3 shared Michael F. SeidliD· 3 shared Petros SkiadasiD· 3 shared Ronnie de JongeiD· 3 shared Femke van den Berg· 1 shared Joris DommisseiD· 1 shared Leroy van der MeeriD· 1 shared

Activity by Year

2024-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 39 mutual co-author links

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3 shared papersGenomics

Guido F. J. M. Van den AckervekenORCID

Mutual co-authors in cluster

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3 papers

Recent·Most cited

GenomicsbioRxivPreprintMay 23, 2025

Evolution of resistance breaking in spinach downy mildew revealed through pangenome graph analysis

Petros Skiadas, Melanie N. Mendel, Joyce Elberse…·Michael F. Seidl

The paper uses pangenome graph analysis of 19 spinach downy mildew isolates to study the evolution of resistance-breaking traits and identifies effector candidates associated with resistance breakdown.

DOI 10.1101/2025.05.23.655769

whole-genome sequencingstatistical model

𝕏 PostBluesky

Plant BiologyMolecular Plant-Microbe InteractionsPeer-reviewedJan 1, 2025

Exploiting Pseudomonas syringae Type 3 secretion to study effector contribution to disease in spinach

Melanie N. Mendel, Xander C. L. Zuijdgeest, Femke van den Berg…·Ronnie de Jonge

This study uses a modified Pseudomonas syringae strain to identify key effectors contributing to disease in spinach, enabling high-throughput analysis of effector function.

3 citations

experimental assayhost-pathogen & immune response

𝕏 PostBluesky

GenomicsPLoS GeneticsPeer-reviewedOct 25, 2024

Pangenome graph analysis reveals extensive effector copy-number variation in spinach downy mildew

Petros Skiadas, Sofía Riera Vidal, Joris Dommisse…·Michael F. Seidl

The paper constructs a pangenome graph for Peronospora effusa, revealing extensive copy-number variation in pathogenicity genes and transposable elements contributing to genomic diversity.

12 citations

plant (other)whole-genome sequencing

𝕏 PostBluesky