Mingyao Li

The paper introduces TASC, a statistical framework to account for technical noise in scRNA-seq by modeling dropout rates and amplification bias, improving differential expression analysis.

The paper introduces SCALE, a method to analyze allele-specific bursting in scRNA-seq data, finding that cis control primarily affects burst frequency.

HadoopCNV detects copy number variants from WGS data using dynamic programming and allelic depth, outperforming existing tools in accuracy and scalability.