Alexandre Blais

This study shows PARKIN is essential for coordinating mitochondrial and nuclear processes in muscle stem cells during regeneration, with loss of PARKIN causing metabolic and RNA processing defects.

The paper shows Mtb infection triggers a type I interferon response through chromatin remodeling, with PPM1A affecting chromatin accessibility and gene expression.

The paper introduces widaR, a method for ATAC-seq differential accessibility analysis that improves sensitivity and resolution by avoiding peak calling and using insertion site counting.

This study identifies Six1's role in regulating MCT10, a thyroid hormone transporter, in skeletal muscle, linking it to fast-twitch muscle gene expression and metabolism.