Author

Andreas G. Hadjigeorgiou

University of CyprusORCID 0000-0003-2484-0074Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cancer Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:drug response / drug discovery· 1 Organism:mouse· 1 Approach:statistical model· 1

Frequent Co-Authors

Lance L. MunniD· 1 shared Rakesh K. JainiD· 1 shared Triantafyllos StylianopoulosiD· 1 shared

Activity by Year

2025-2025 · peak 1/yr

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3 top collaborators · 3 mutual co-author links

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1 shared paperCancer Biology

Lance L. MunnORCID

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1 paper

Recent·Most cited

Cancer BiologyProceedings of the National Academy of SciencesPeer-reviewedNov 11, 2025

Physiologically-based pharmacokinetic model for CAR-T cells delivery and efficacy in solid tumors

Andreas G. Hadjigeorgiou, Lance L. Munn, Triantafyllos Stylianopoulos, Rakesh K. Jain

The paper develops a physiologically based pharmacokinetic model to simulate CAR-T cell dynamics in solid tumors, showing vascular normalization improves efficacy and reduces required CAR-T doses.

15 citationstop 2%

mousestatistical model

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