Author

John C. Mansfield

National Health ServiceORCID 0000-0003-2490-7750Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Genetic & Genomic Medicine· 1 Genetics· 1 Genomics· 1

Signature Assays, Organisms & Methods

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Organism:human· 3 Approach:statistical model· 3 Research Focus:GWAS / association mapping· 2 Assay:whole-exome sequencing· 2 Research Focus:fine-mapping· 1 Research Focus:variant effect prediction· 1

Frequent Co-Authors

Jeffrey C. BarrettiD· 3 shared Aleksejs SazonovsiD· 2 shared Daniel L RiceiD· 2 shared Graham HeapiD· 2 shared Natalie J. PrescottiD· 2 shared Peter Miles IrvingiD· 2 shared Tariq AhmadiD· 2 shared Aarno V. PalotieiD· 1 shared

Activity by Year

2017-2022 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 42 mutual co-author links

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3 shared papersGenetic & Genomic Medicine

Jeffrey C. BarrettORCID

Mutual co-authors in cluster

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3 papers

Recent·Most cited

Genetic & Genomic MedicineNature GeneticsPeer-reviewedAug 29, 2022

Sequencing of over 100,000 individuals identifies multiple genes and rare variants associated with Crohns disease susceptibility

Aleksejs Sazonovs, Christine R. Stevens, Guhan Ram Venkataraman…·Rasha Shawky

The paper identifies ten new genes with coding variants linked to Crohn's disease risk using sequencing data from over 30,000 patients and 80,000 controls.

197 citationstop 1%

humanwhole-exome sequencing

𝕏 PostBluesky

GenomicsGastroenterologyPeer-reviewedOct 7, 2019

HLA-DQA1*05 is associated with the development of antibodies to anti-TNF therapy

Aleksejs Sazonovs, Nicholas Alexander Kennedy, Loukas Moutsianas…·Thankam Paul

This study identifies HLA-DQA1*05 as a genetic risk factor for anti-drug antibody development in Crohn's disease patients treated with anti-TNF therapies.

424 citationstop 1%

humanstatistical model

𝕏 PostBluesky

GeneticsJournal of Crohn s and ColitisPeer-reviewedDec 1, 2017

Exome sequencing and genotyping identify a rare variant in NLRP7 gene associated with ulcerative colitis.

Alexandros Onoufriadis, Kristina L. Stone, Antreas Katsiamides…·Natalie J. Prescott

The paper identifies a rare variant in the NLRP7 gene associated with increased risk of ulcerative colitis through exome sequencing and genotyping in IBD families and cohorts.

22 citations

humanwhole-exome sequencing

𝕏 PostBluesky