Author

Daniel L Rice

Wellcome Sanger InstituteORCID 0000-0002-2972-0365Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Genomics· 2 Bioinformatics· 1 Genetic & Genomic Medicine· 1 Genetics· 1

Signature Assays, Organisms & Methods

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Approach:statistical model· 5 Research Focus:GWAS / association mapping· 4 Organism:human· 4 Assay:GWAS summary statistics· 2 Research Focus:cell type annotation· 1 Research Focus:clustering· 1 Research Focus:database / resource· 1 Research Focus:dimensionality reduction· 1

Frequent Co-Authors

Graham HeapiD· 3 shared Jeffrey C. BarrettiD· 3 shared Tariq AhmadiD· 3 shared Aleksejs SazonovsiD· 2 shared Craig MowatiD· 2 shared John C. MansfieldiD· 2 shared Loukas MoutsianasiD· 2 shared Miles ParkesiD· 2 shared

Activity by Year

2016-2022 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 42 mutual co-author links

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3 shared papersGenomics

Graham HeapORCID

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Author profile →

5 papers

Recent·Most cited

BioinformaticsBioinformaticsPeer-reviewedDec 9, 2022

Annotation of biologically relevant ligands in UniProtKB using ChEBI

Elisabeth Coudert, Sébastien Géhant, Edouard de Castro…·Elena Speretta

The paper reannotates ligand binding sites in UniProtKB using ChEBI identifiers and improves search facilities for these annotations.

350 citationstop 1%

protein sequencestatistical model

𝕏 PostBluesky

Genetic & Genomic MedicineNature GeneticsPeer-reviewedAug 29, 2022

Sequencing of over 100,000 individuals identifies multiple genes and rare variants associated with Crohns disease susceptibility

Aleksejs Sazonovs, Christine R. Stevens, Guhan Ram Venkataraman…·Rasha Shawky

The paper identifies ten new genes with coding variants linked to Crohn's disease risk using sequencing data from over 30,000 patients and 80,000 controls.

197 citationstop 1%

humanwhole-exome sequencing

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GenomicsGastroenterologyPeer-reviewedOct 7, 2019

HLA-DQA1*05 is associated with the development of antibodies to anti-TNF therapy

Aleksejs Sazonovs, Nicholas Alexander Kennedy, Loukas Moutsianas…·Thankam Paul

This study identifies HLA-DQA1*05 as a genetic risk factor for anti-drug antibody development in Crohn's disease patients treated with anti-TNF therapies.

424 citationstop 1%

humanstatistical model

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GeneticsNaturePeer-reviewedSep 25, 2018

Common genetic variants contribute to risk of rare severe neurodevelopmental disorders

Mari Niemi, Hilary C. Martin, Daniel L Rice…·Jeffrey C. Barrett

The paper shows that common genetic variants contribute to risk and clinical variation in severe neurodevelopmental disorders, even in individuals with known monogenic diagnoses.

340 citationstop 1%

humanGWAS summary statistics

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GenomicsbioRxivJun 10, 2016

Genome-wide association study implicates immune activation of multiple integrin genes in inflammatory bowel disease

Katrina M de Lange, Loukas Moutsianas, James C Lee…·Jeffrey Barrett

This study identifies 26 new genetic loci associated with inflammatory bowel disease, including integrin genes linked to immune activation and disease risk.

DOI 10.1038/ng.3760

humanGWAS summary statistics

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