Author

Graham Heap

National Health ServiceORCID 0000-0003-4131-6792Unclaimed ORCID profile · follow to get notified of new preprints

Additional preprints under this name without ORCID

Graham Heap1 paper

Biology Disciplines

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Genomics· 2 Genetic & Genomic Medicine· 1

Signature Assays, Organisms & Methods

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Research Focus:GWAS / association mapping· 3 Organism:human· 3 Approach:statistical model· 3 Research Focus:fine-mapping· 1 Assay:GWAS summary statistics· 1 Assay:whole-exome sequencing· 1

Frequent Co-Authors

Daniel L RiceiD· 3 shared Tariq AhmadiD· 3 shared Aleksejs SazonovsiD· 2 shared Craig MowatiD· 2 shared Jeffrey C. BarrettiD· 2 shared John C. MansfieldiD· 2 shared Loukas MoutsianasiD· 2 shared Miles ParkesiD· 2 shared

Activity by Year

2016-2022 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 42 mutual co-author links

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3 shared papersGenomics

Daniel L RiceORCID

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3 papers

Recent·Most cited

Genetic & Genomic MedicineNature GeneticsPeer-reviewedAug 29, 2022

Sequencing of over 100,000 individuals identifies multiple genes and rare variants associated with Crohns disease susceptibility

Aleksejs Sazonovs, Christine R. Stevens, Guhan Ram Venkataraman…·Rasha Shawky

The paper identifies ten new genes with coding variants linked to Crohn's disease risk using sequencing data from over 30,000 patients and 80,000 controls.

197 citationstop 1%

humanwhole-exome sequencing

𝕏 PostBluesky

GenomicsGastroenterologyPeer-reviewedOct 7, 2019

HLA-DQA1*05 is associated with the development of antibodies to anti-TNF therapy

Aleksejs Sazonovs, Nicholas Alexander Kennedy, Loukas Moutsianas…·Thankam Paul

This study identifies HLA-DQA1*05 as a genetic risk factor for anti-drug antibody development in Crohn's disease patients treated with anti-TNF therapies.

424 citationstop 1%

humanstatistical model

𝕏 PostBluesky

GenomicsbioRxivJun 10, 2016

Genome-wide association study implicates immune activation of multiple integrin genes in inflammatory bowel disease

Katrina M de Lange, Loukas Moutsianas, James C Lee…·Jeffrey Barrett

This study identifies 26 new genetic loci associated with inflammatory bowel disease, including integrin genes linked to immune activation and disease risk.

DOI 10.1038/ng.3760

humanGWAS summary statistics

𝕏 PostBluesky