Author

Xindong Chen

Tsinghua UniversityORCID 0000-0003-2498-1280Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Research Focus:cell signaling & trafficking· 2 Approach:mechanistic / dynamical model· 2 Research Focus:cancer & tumor microenvironment· 1

Frequent Co-Authors

Xi-Qiao FengiD· 2 shared Bo LiiD· 1 shared Huiyan Liang· 1 shared Wei Ping FangiD· 1 shared Zhongya LiniD· 1 shared

Activity by Year

2025-2025 · peak 2/yr

Co-Author Collaboration Network

5 top collaborators · 7 mutual co-author links

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2 shared papersBiophysics

Xi-Qiao FengORCID

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2 papers

Recent·Most cited

BiophysicsACS NanoPeer-reviewedDec 30, 2025

Adaptive cytoskeletal responses to extracellular environment viscosity modulate cell migration

Zhongya Lin, Xindong Chen, Xi-Qiao Feng

This study develops a mechanobiological model to show how extracellular viscosity affects cancer cell migration through actin dynamics and adhesion, revealing a biphasic response and migration memory.

8 citations

mechanistic / dynamical modelcell signaling & trafficking

𝕏 PostBluesky

BiophysicsbioRxivPreprintSep 5, 2025

Multiscale modeling of cell-substrate adhesion dynamics: effects of integrin activation, clustering and internalization

Huiyan Liang, Wei Ping Fang, Xindong Chen…·Xi‐Qiao Feng

This study develops a multiscale model to explore how integrin activation, clustering, and internalization influence cell-substrate adhesion dynamics and migration behavior.

DOI 10.1101/2025.09.05.674169

mechanistic / dynamical modelcell signaling & trafficking

𝕏 PostBluesky