Author

Isaac Francos-Quijorna

Consejo Superior de Investigaciones CientíficasORCID 0000-0003-2514-4206Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Immunology· 1 Molecular Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:mouse· 2 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1

Frequent Co-Authors

Álvaro Fernández-AlmeidaiD· 2 shared Elisa CarrascoiD· 2 shared Enrique Gabandé‐RodrígueziD· 2 shared Gonzalo Soto‐HerederoiD· 2 shared José Ignacio Escrig-LarenaiD· 2 shared Manuel M. Gómez de las HerasiD· 2 shared Marı́a MittelbrunniD· 2 shared Pablo Ramírez-Ruiz de ErenchuniD· 2 shared

Activity by Year

2026-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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2 shared papersImmunology

Álvaro Fernández-AlmeidaORCID

Mutual co-authors in cluster

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2 papers

Recent·Most cited

ImmunologyNature AgingPeer-reviewedAug 26, 2026

Cytotoxic CD4+ T cells in the bone marrow compromise healthy ageing by enhancing granulopoiesis

Enrique Gabandé‐Rodríguez, Gonzalo Soto‐Heredero, Elisa Carrasco…·María Mittelbrunn

This study identifies CD4+ cytotoxic T cells in the bone marrow that enhance granulopoiesis in aged mice, contributing to age-related diseases and showing that CCR5 inhibition can mitigate these effects.

2 citations

mousebulk RNA-seq

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Molecular BiologyNature CommunicationsPeer-reviewedMar 13, 2026

Butyrate extends health and lifespan in mice with mitochondrial deficiency

Enrique Gabandé‐Rodríguez, Manuel M. Gómez de las Heras, Pablo Ramírez-Ruiz de Erenchun…·Marı́a Mittelbrunn

This study shows that butyrate supplementation improves health and extends lifespan in mice with mitochondrial dysfunction by restoring intestinal barrier function and epigenetic marks.

6 citationstop 1%

mouseexperimental assay

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