Marı́a Mittelbrunn

This study shows that butyrate supplementation improves health and extends lifespan in mice with mitochondrial dysfunction by restoring intestinal barrier function and epigenetic marks.

This study identifies the HBP-ISR axis as a driver of thoracic aortic aneurysm in Marfan Syndrome, showing that targeting this pathway can reverse aortic dilation in mice and is associated with human TAAD.