Author

Carlos Jesus Perez Kerkvliet

University of MinnesotaORCID 0000-0003-2530-840XUnclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cancer Biology· 1

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Organism:human· 1 Approach:statistical model· 1

Frequent Co-Authors

Amy R. DwyeriD· 1 shared Carol Ann LangeiD· 1 shared Ellie Piepgras· 1 shared Geoffrey L. GreeneiD· 1 shared Julie Hanson OstranderiD· 1 shared Kyla M. Hagen· 1 shared Noelle E. GillisiD· 1 shared Nuri A. TemiziD· 1 shared

Activity by Year

2026-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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1 shared paperCancer Biology

Amy R. DwyerORCID

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1 paper

Recent·Most cited

Cancer Biologynpj Breast CancerPeer-reviewedApr 7, 2026

Progesterone receptors drive advanced breast cancer phenotypes including circulating tumor- and stem-like cell expansion in the context of ESR1 mutation

Thu Ha Truong, Noelle E. Gillis, Amy R. Dwyer…·Carol Ann Lange

This study shows that progesterone receptors (PR) interact with mutant ESR1 variants in ER+ breast cancer, driving CSC expansion and UPR activation, which can be targeted therapeutically.

DOI 10.1038/s41523-026-00939-8

humanbulk RNA-seq

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