Julie Hanson Ostrander

This study shows that CDH1 loss in human mammary epithelial cells remodels gene expression and lineage identity toward a luminal progenitor-like state, contributing to ILC oncogenesis.

This study develops novel oncolytic viruses derived from T1L mammalian orthoreovirus that enhance killing of therapy-resistant breast cancer stem-like cells.

This study shows that progesterone receptors (PR) interact with mutant ESR1 variants in ER+ breast cancer, driving CSC expansion and UPR activation, which can be targeted therapeutically.

This study develops a metastatic ILC mouse model to study organ tropism, endocrine response, and bone remodeling in mILC.

This study shows that 27HC-treated neutrophils release sEVs that induce EMT and stemness in breast cancer cells via WNT/β-catenin pathway activation.

The paper investigates how PR-A and PR-B isoforms regulate divergent gene expression and phenotypes in breast cancer cells, showing PR-A is linked to poor clinical outcomes.