Benjamin Adam Samuels

This study examines how diet-induced obesity and chronic stress interact in a mouse model of menopause, showing increased cognitive impairments and metabolic changes in VCD-treated HFD-fed mice.

This study shows female and male mice are equally susceptible to chronic non-discriminatory social defeat stress, despite females receiving fewer attacks, and that susceptibility correlates with impaired reward valuation.

This study shows that the 16p11.2 microdeletion worsens neurodevelopmental issues caused by early-life antibiotic exposure, affecting gut microbiota, hippocampal development, and behavior.

This study examines how chronic social instability stress affects behavior and transcriptome in male and female mice, revealing sex-specific differences in stress response and gene expression in the anterodorsal BNST.

This study identifies a compound that enhances adult hippocampal neurogenesis and improves behavioral pattern separation in both young and aged mice.

This study shows chronic stress causes sex-dependent transcriptome changes in the anterodorsal BNST, with males showing RNA processing gene bias and females showing synaptic transmission gene bias, along with sex-specific electrophysiological effects.

The paper shows that activating CRF+ neurons in the aBNST reduces effortful motivation behaviors in mice during reward tasks.

This study identifies Activin signaling in the dentate gyrus as a key mediator of antidepressant response, showing that modulating it can convert non-responders to responders and vice versa.

This study examines how fluoxetine affects behavior and adult hippocampal neurogenesis in female mice across the estrous cycle, finding phase-specific effects.

This study shows chronic corticosterone administration in mice increases anxiety-like behaviors and impairs reward-related behaviors, suggesting it models stress-induced mood disorders.

This paper introduces a social stress paradigm, social instability stress (SIS), that induces chronic stress in both male and female mice, with effects reversible by antidepressants.

This study investigates how chronic stress affects CRH signaling and neuronal activity in the BNST, linking these changes to anxiety-related behaviors in mice.