Author

Wei-li Chang

Centre for Addiction and Mental HealthORCID 0009-0003-5377-2522Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Neuroscience· 2 Animal Behavior & Cognition· 1

Signature Assays, Organisms & Methods

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Organism:mouse· 3 Research Focus:differential expression· 2 Approach:experimental assay· 2 Assay:behavioral assay· 1 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:cell-cell communication· 1 Research Focus:host-pathogen & immune response· 1

Frequent Co-Authors

René HeniD· 3 shared Karly Tegang· 2 shared Adrienne N. SantiagoiD· 1 shared Angélique Augustin· 1 shared Benjamin A. SamuelsiD· 1 shared Clay LacefieldiD· 1 shared Denis Joseph Paul DavidiD· 1 shared Doris RothiD· 1 shared

Activity by Year

2024-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 26 mutual co-author links

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3 shared papersNeuroscience

René HenORCID

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3 papers

Recent·Most cited

NeuroscienceNeuropsychopharmacologyPeer-reviewedFeb 4, 2026

Effects of electroconvulsive shock on the function, circuitry, and transcriptome of dentate gyrus granule neurons

Adrienne N. Santiago, Julia Castello Saval, Phi Nguyen…·Wei-li Chang

This study shows ECS-induced neurogenesis is necessary for antidepressant effects and identifies transcriptomic changes in granule neurons.

3 citationstop 3%

mousebulk RNA-seq

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NeurosciencebioRxivPreprintMar 7, 2025

Distinct representations of an anxiogenic environment in different cell types of the ventral hippocampus

Jack E. Berry, Jessica Jimenez, Kenechukwu Michael Ogbu…·Wei-li Chang

The paper examines how different cell types in the ventral hippocampus encode anxiety-related information during an anxiety test, finding distinct encoding patterns in granule cells and mossy cells.

DOI 10.1101/2025.03.07.641976

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Animal Behavior & CognitionBiological Psychiatry Global Open SciencePeer-reviewedNov 20, 2024

Pharmacological Enhancement of Adult Hippocampal Neurogenesis Improves Behavioral Pattern Separation in Young and Aged Mice

Wei-li Chang, Karly Tegang, Benjamin A. Samuels…·René Hen

This study identifies a compound that enhances adult hippocampal neurogenesis and improves behavioral pattern separation in both young and aged mice.

10 citations

mousebehavioral assay

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