Aaron J. Kucinski

This study shows that combining optogenetic inhibition of basal forebrain cholinergic neurons with striatal dopamine depletion in rats increases fall vulnerability on balance beam tasks.

This study shows that TAK-071, an M1 PAM, improves attentional performance in rats with cholinergic losses, particularly in recovery after distractors.

This study shows that mice with reduced cholinergic capacity experience severe, lasting attention impairments after repeated mild concussions, suggesting similar risks in humans with vulnerable cholinergic systems.