Author

Miriam A. Schiele

University of FreiburgORCID 0000-0003-2613-6515Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Organism:human· 2 Approach:statistical model· 2 Research Focus:benchmarking· 1 Research Focus:differential expression· 1 Assay:DNA methylation· 1 Assay:electronic health records· 1

Frequent Co-Authors

Katharina DomschkeiD· 2 shared André Tadić· 1 shared Andreas ReifiD· 1 shared David P. HerzogiD· 1 shared Dirk SchümanniD· 1 shared Elisabeth Johanna LeehriD· 1 shared Eric Zillich· 1 shared Fabian StreitiD· 1 shared

Activity by Year

2025-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 27 mutual co-author links

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2 shared papersGenomics

Katharina DomschkeORCID

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2 papers

Recent·Most cited

GenomicsbioRxivPreprintNov 20, 2025

Dynamic Epigenetic Changes During Antidepressant Pharmacotherapy in Major Depressive Disorder

Svenja Müller, Josef Frank, Eric Zillich…·Lea Zillich

This study identifies DNA methylation changes over time during antidepressant treatment in MDD, linking them to neuroplasticity and inflammation, and shows differences between responders and non-responders.

DOI 10.1101/2025.11.20.688229

humanDNA methylation

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NeuroscienceeLifePeer-reviewedFeb 20, 2025

Reduced discrimination between signals of danger and safety but not overgeneralization is linked to exposure to childhood adversity in healthy adults

Maren Klingelhöfer-Jens, Katharina Hutterer, Miriam A. Schiele…·Tina B. Lonsdorf

The paper examines how childhood adversity affects threat learning in healthy adults, finding reduced discrimination between danger and safety signals but not overgeneralization.

11 citations

humanelectronic health records

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