Andreas Reif

This study conducts a genome-wide association analysis of generalised anxiety symptom severity, identifying 80 significant variants and showing genetic correlations with other mental and physical health traits.

The paper examines how childhood adversity affects threat learning in healthy adults, finding reduced discrimination between danger and safety signals but not overgeneralization.

This study shows that external cues improve visual working memory in schizophrenia when salient distractors are present, suggesting preserved top-down attention guidance despite attentional control deficits.

This study shows that cortex-based macroanatomical alignment improves the consistency and statistical power of fMRI visual field localizer data in group analyses.

This study investigates the genetic contribution of dopaminergic and serotonergic pathways to eight psychiatric disorders using GWAS data from the Psychiatric Genomics Consortium.

This study analyzes structural brain asymmetries in ADHD using 39 datasets, finding small effects that do not meet study-wide significance thresholds.

The paper reports exome sequencing findings in bipolar disorder, identifying AKAP11 as a shared risk gene with schizophrenia through ultra-rare protein-truncating variants.

This study uses machine learning to show that structural brain anomalies in ADHD are similar in children and adults, supporting continuity of the disorder's pathophysiology.

The paper identifies genetic loci associated with brainstem volumes and finds genetic overlaps with psychiatric and neurological disorders.

This study identifies nine new genetic loci associated with ADHD and shows shared genetic architecture between childhood and adult ADHD.

This study identifies dopaminergic signaling as a genetic link between ADHD and obesity through genome-wide analyses and brain volume associations.

The paper investigates how genetic variation in DRD4 interacts with seasonal daylight changes to influence inattention, finding support for the Spring-focus hypothesis and seasonal patterns in ADHD-related symptoms.

Genome-wide association meta-analysis of 20,183 ADHD cases and 35,191 controls finds 12 significant loci; signal concentrates in conserved regions, constrained genes, and CNS regulatory elements.

The paper shows that polygenic scores for depression traits predict lithium response in bipolar disorder patients, with lower genetic load linked to better treatment outcomes.

This paper conducts a GWAS on suicide attempt across psychiatric disorders, identifying genetic loci and showing polygenic risk for major depression predicts suicide attempt in multiple disorders.

This study finds that a higher genetic risk for schizophrenia is linked to poorer lithium response in bipolar disorder patients, suggesting potential for personalized treatment strategies.