Changshun Shao

This study uses spatial multi-omics to identify myeloid cell subsets and their functional roles in human atherosclerotic plaques, linking ECM and lipid cues to macrophage state transitions.

This study shows that switching CD47 isoforms from full-length to truncated in ovarian cancer cells triggers macrophage-mediated pyroptosis and reduces tumor growth.

This study combines imaging mass cytometry and single-cell RNA sequencing to analyze the spatial and temporal dynamics of cell interactions and phenotypes in atherosclerotic plaques.