Derrick Brazill

This paper develops a mathematical model of bleb expansion to show that TalA regulates intracellular pressure by limiting membrane expansion during blebbing, resulting in smaller and less frequent blebs in its absence.

The paper predicts nucleation sites in chemotaxing Dictyostelium discoideum using an energy functional based on membrane geometry and pressure differentials, achieving 96.8% accuracy when restricted to the expected bleb region.