Devin Kwok

This paper shows that combining feature selection and aggregation in GReX limits TWAS power and adaptability, especially with low expression heritability.

kTWAS combines TWAS feature selection with SKAT kernel methods to improve statistical power and identify novel disease-associated genes.

This paper compares the power of GWAS, TWAS, and a hypothetical real expression protocol to determine when TWAS is effective and when GWAS is better.

PoolHapX reconstructs microbial haplotypes by integrating genetic sharing and genomic sequencing, outperforming existing tools and revealing new insights into HIV evolution.