Reconstruction of microbial haplotypes by integration of statistical and physical linkage in scaffolding
Chen Cao, Jingni He, Lauren Mak, Deshan Perera, Devin Kwok, Jia Wang, Minghao Li, Tobias Mourier, Stefan Gavriliuc, Matthew Greenberg, A. Sorana Morrissy, Laura K. Sycuro, Guang Yang, Daniel Charlton Jeffares, Quan Long
PoolHapX reconstructs microbial haplotypes by integrating genetic sharing and genomic sequencing, outperforming existing tools and revealing new insights into HIV evolution.
bioRxiv · Mar 29, 2020 · PreprintBioinformatics