Ivan Vito Ferrari

This study evaluates the binding of natural compounds to PCSK9 mutants using molecular docking and in silico analysis, identifying Hypericin as a promising candidate for cholesterol management.

The paper reports an in silico docking study showing Telatinib has strong binding affinity to Plasmodium falciparum thioredoxin reductase, comparable to the crystallized ligand FAD.

The paper uses open-access in silico tools to predict ADMET profiles and bioactivity of garlic compounds, identifying promising bioactive molecules.

The paper identifies potential aldosterone antagonists using in silico docking analysis with AutoDock Vina and AutoDock 4, finding a drug with high binding affinity similar to spironolactone.

The paper evaluates Paritaprevir as a potential drug against Mtb using in silico docking and finds it has favorable binding affinity and Ki values comparable to existing drugs.

The paper validates molecular docking analysis of human serum albumin with six ligands, identifying 9-amino-camptothecin, camptothecin, and teniposide as top binders based on binding affinity and RMSD values.

The paper compares BLAST and Clustal-X alignments of monoclonal antibody light and heavy chains to assess sequence homology and identify conserved regions.