Heeyoung Seok

This study uses base editing to correct a mutation causing hearing loss in a humanized mouse model, restoring hearing function and gene expression.

This study uses multiplexed imaging to analyze immune and stromal cell changes in abdominal aortic aneurysms (AAAs) based on C-reactive protein (CRP) levels, revealing distinct immune cell distributions and macrophage phenotypes associated with CRP deposition.

The paper develops CRISPR-based strategies to correct a complex genomic rearrangement in EYA1 linked to haploinsufficiency, showing successful gene expression restoration in patient-derived cells.