Author
Seoul National UniversityORCID 0000-0002-6206-4937Unclaimed ORCID profile · follow to get notified of new preprints
Mutual co-authors in cluster
4 papers
Recent·Most cited
Sang‐Yeon Lee, Seungbok Lee, Seongyeol Park…·Jong‐Hee Chae
This study uses whole-genome sequencing and functional assays to improve genetic diagnosis of sensorineural hearing loss, achieving a 55.6% diagnostic yield through comprehensive genomic profiling.
Shao Wei Hu, Sohyang Jeong, Luoying Jiang…·Yilai Shu
This study uses base editing to correct a mutation causing hearing loss in a humanized mouse model, restoring hearing function and gene expression.
Yi Hwalin, Yejin Yun, Won Hoon Choi…·Daesik Kim
The paper develops CRISPR-based strategies to correct a complex genomic rearrangement in EYA1 linked to haploinsufficiency, showing successful gene expression restoration in patient-derived cells.
Ju Hyuen Cha, Seok‐Hoon Lee, Yejin Yun…·Sang‐Yeon Lee
This study corrects a SSBP1 mutation using adenine base editors, improving mitochondrial function but with trade-offs between editing efficacy and off-target risks.