Péter Buchwald

This study examines how immunosuppressive drugs affect glucose-stimulated insulin secretion using dynamic perifusion assays, finding concentration-dependent inhibition with varying patterns among drug types.

This study investigates the rate-dependence of the first phase of glucose-stimulated insulin secretion using dynamic perifusion of human pancreatic islets, finding it follows a sigmoid function of the glucose gradient.

The paper introduces the Kd/EC50 ratio as a gain parameter to quantify signal amplification for full agonists, clarifying the relationship between receptor occupancy and response.

The paper validates 12 biomarkers from a small T1D cohort using data augmentation, identifying 7 significantly altered markers linked to T1D risk.