Author

Laising Yen

Baylor College of MedicineORCID 0000-0003-2746-414XUnclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Bioinformatics· 1 Cancer Biology· 1 Synthetic Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:gene regulatory network inference· 3 Approach:experimental assay· 2 Organism:human· 2 Research Focus:benchmarking· 1 Research Focus:cell type annotation· 1 Research Focus:chromatin & epigenetic regulation· 1 Research Focus:drug response / drug discovery· 1 Assay:long-read sequencing· 1

Frequent Co-Authors

Liming LuoiD· 2 shared Sachin Kumar GuptaiD· 2 shared Chia-Ying CheniD· 1 shared Chih-Fan ChuangiD· 1 shared Jocelyn Duen-Ya JeaiD· 1 shared Pei-Wen Chao· 1 shared Te‐Lun MaiiD· 1 shared Trees‐Juen ChuangiD· 1 shared

Activity by Year

2017-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 22 mutual co-author links

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2 shared papersSynthetic Biology

Liming LuoORCID

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3 papers

Recent·Most cited

Synthetic BiologybioRxivPreprintJan 27, 2023

pA regulator: a system for controlling mammalian gene expression via the modulation of polyA signal cleavage

Liming Luo, Jocelyn Duen-Ya Jea, Yan Wang…·Laising Yen

The paper introduces a non-immunogenic RNA-based gene regulation system called pA regulator that controls gene expression via polyA signal cleavage with high efficiency and reversibility.

2 citations

mouseexperimental assay

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BioinformaticsGenome ResearchPeer-reviewedMar 1, 2020

Genome-wide, integrative analysis implicates circular RNA dysregulation in autism and the corresponding circular RNA-microRNA-mRNA regulatory axes

Yen‐Ju Chen, Chia-Ying Chen, Te‐Lun Mai…·Trees‐Juen Chuang

The paper identifies circRNA dysregulation in ASD and links it to circRNA-microRNA-mRNA regulatory networks involving ASD risk genes.

70 citations

humanlong-read sequencing

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Cancer BiologybioRxivPreprintJun 16, 2017

RNA-mediated Genomic Arrangements in Mammalian Cells

Sachin Kumar Gupta, Liming Luo, Laising Yen

This study shows that chimeric RNA expression can drive genomic rearrangements leading to gene fusions in mammalian cells, challenging the 'cart before the horse' hypothesis.

DOI 10.1101/151241

humanmultiome

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