Kern Rei Chng

The paper analyzes gut metagenomes of Asian octogenarians to identify age-related microbial shifts and their associations with aging phenotypes.

The paper characterizes the ecological and evolutionary dynamics of gut microbiomes colonized by carbapenemase-producing Enterobacteriaceae (CPE) using longitudinal metagenomics and whole genome sequencing.

BEEM-Static infers ecological interactions from metagenomic data, outperforming existing methods in detecting interaction directionality and robustness to non-steady-state samples.

The paper identifies specific bacterial species associated with gut microbiome recovery after antibiotic use and shows their role in promoting microbial diversity and preventing pathogen colonization.

INC-Seq improves nanopore sequencing accuracy for bacterial profiling using intramolecular-ligated consensus sequencing, achieving >97% median accuracy for 16S rRNA amplicons.