Jani Huuhtanen

PAIR-Scan identifies potent TCR-neoantigen pairs from tumor samples through library-on-library screening, enabling efficient analysis of T cell reactivity.

This paper develops SMART-PTA for single-cell whole-genome and transcriptome sequencing, revealing clonal evolution in aged human esophageal tissue over 70 years.

TCRconv predicts T-cell receptor-epitope recognition using a deep learning model and provides insights into T-cell dynamics in COVID-19 patients.

The paper introduces TCRGP, a Gaussian process method for predicting TCR epitope specificity, and applies it to scRNA+TCRβ data to identify HBV-epitope specific T cells in hepatocellular carcinoma patients.