Author
Vanderbilt University Medical CenterORCID 0000-0003-2771-6466Unclaimed ORCID profile · follow to get notified of new preprints
Mutual co-authors in cluster
5 papers
Recent·Most cited
M. Lorena Harvey, Ellen M Osborn, Megan Cummins Lancaster…·Andrew Michael Glazer
The paper maps the functional landscape of KCNQ1 variants to identify pathogenic and benign variants, revealing their impact on arrhythmia risk and ion channel mechanisms.
Devyn Mitchell, Rizwan Ullah, Loren R. Vanags…·Brett M. Kroncke
The paper generates hiPSC lines from patients with extreme polygenic scores for QT interval to study LQTS genetic and cellular complexity.
Megan Cummins Lancaster, Giovanni Davogustto, Edi Prifti…·Joe‐Elie Salem
The paper develops a polygenic risk score for baseline QTc and shows it predicts sotalol-induced QT prolongation in a cohort of healthy subjects.
Joanne G. Ma, Matthew J. O’Neill, Ebony Richardson…·Andrew Michael Glazer
The paper validates an in vitro SCN5A Brugada Syndrome assay to reclassify variants of uncertain significance as pathogenic or benign.
Andrew Michael Glazer, Giovanni Davogustto, Christian M. Shaffer…·Dan M. Roden
The paper identifies pathogenic variants in arrhythmia genes in eMERGE-III participants and reclassifies variants of uncertain significance using functional studies.