Antibody evasion and receptor binding of SARS-CoV-2 LP.8.1.1, NB.1.8.1, XFG, and related subvariants
Ian A. Mellis, Madeline Wu, Hsiang Hong, Chih-Chen Tzang, Anthony D. Bowen, Qian Wang, Carmen Gherasim, Virginia Pierce, Jayesh Shah, Lawrence J. Purpura, Michael T. Yin, Aubree L. Gordon, Yicheng Guo, David D. Ho
This study compares antibody evasion and receptor binding of SARS-CoV-2 subvariants, finding that LP.8.1.1 has high ACE2 affinity, while NB.1.8.1 and XFG show greater antibody evasion.
Cell Reports · Nov 24, 2025Peer-reviewedMicrobiology