Sally L. George

Pheno-MYCN links slide-level MYCN prediction to interpretable morphological sub-populations in neuroblastoma, revealing a continuous gradient of MYCN-associated features.

This study develops a neuroblastoma mouse model to investigate chemotherapy resistance and immune evasion mechanisms, identifying CDK8 upregulation and immune cell infiltration as key factors.

This study shows that ATRX mutation type affects chromatin response to retinoic acid in neuroblastoma, influencing differentiation and therapeutic response.

The paper develops a targeted sequencing panel for paediatric solid tumours and validates its sensitivity and specificity across various sample types.