Author

Luan Nguyen

University Medical Center UtrechtORCID 0000-0003-2788-6625Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Genomics· 2 Genetic & Genomic Medicine· 1

Signature Assays, Organisms & Methods

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Organism:human· 3 Research Focus:variant calling· 3 Assay:whole-genome sequencing· 3 Approach:statistical model· 2 Research Focus:benchmarking· 1 Research Focus:database / resource· 1 Research Focus:differential expression· 1 Research Focus:genome assembly· 1

Frequent Co-Authors

Arne van HoeckiD· 3 shared Edwin P. J. G. CuppeniD· 3 shared Ali MovasatiiD· 1 shared Chris J. de WitteiD· 1 shared Christa van Schaik-van de Mheen· 1 shared Francisco Martínez-JiméneziD· 1 shared Ingrid A BoereiD· 1 shared Joachim KutzeraiD· 1 shared

Activity by Year

2022-2022 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 33 mutual co-author links

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3 shared papersGenomics

Arne van HoeckORCID

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3 papers

Recent·Most cited

GenomicsNature CommunicationsPeer-reviewedJul 11, 2022

Machine learning-based tissue of origin classification for cancer of unknown primary diagnostics using genome-wide mutation features

Luan Nguyen, Arne van Hoeck, Edwin P. J. G. Cuppen

The paper develops a random forest classifier using genome-wide mutation features to classify cancer of unknown primary (CUP) with high accuracy.

84 citationstop 2%

humanwhole-genome sequencing

𝕏 PostBluesky

GenomicsbioRxivPreprintJun 17, 2022

Pan-cancer whole genome comparison of primary and metastatic solid tumors

Francisco Martínez-Jiménez, Ali Movasati, Sascha R. Brunner…·Arne van Hoeck

This study compares whole-genome sequences of primary and metastatic tumors across 7,152 samples, revealing cancer-type-specific genomic changes and treatment-induced evolutionary bottlenecks.

15 citations

humanwhole-genome sequencing

𝕏 PostBluesky

Genetic & Genomic MedicineCancersPeer-reviewedMar 15, 2022

Distinct genomic profiles are associated with treatment response and survival in ovarian cancer

Chris J. de Witte, Joachim Kutzera, Arne van Hoeck…·Petronella Oda Witteveen

This study identifies genomic subgroups in ovarian cancer associated with distinct treatment responses and survival outcomes using whole genome sequencing data.

12 citations

humanwhole-genome sequencing

𝕏 PostBluesky