Author

Ali Movasati

University of ZurichORCID 0000-0002-2178-4110Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Evolutionary Biology· 1 Genomics· 1 Molecular Biology· 1

Signature Assays, Organisms & Methods

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Organism:human· 3 Approach:statistical model· 2 Research Focus:variant calling· 2 Assay:whole-genome sequencing· 2 Assay:CRISPR screen· 1 Research Focus:differential expression· 1 Approach:experimental assay· 1 Research Focus:genome assembly· 1

Frequent Co-Authors

Karin Jutta MetzneriD· 2 shared Adriana L. HotziD· 1 shared Arne van HoeckiD· 1 shared Christine Leemann· 1 shared D. Rodrigues· 1 shared Edwin P. J. G. CuppeniD· 1 shared Francisco Martínez-JiméneziD· 1 shared Jurek Andres· 1 shared

Activity by Year

2022-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 16 mutual co-author links

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2 shared papersMolecular Biology

Karin Jutta MetznerORCID

Mutual co-authors in cluster

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3 papers

Recent·Most cited

DNA Damage Response Proteins Are Involved in the Formation of Defective HIV-1 Proviruses

Koleta Michalek, Sagnik Bhattacharjee, Ali Movasati, V. Clerc, Jurek Andres, Adriana L. Hotz, D. Rodrigues, Karin Jutta Metzner

This study identifies DNA damage response proteins that influence the formation of defective HIV-1 proviruses through CRISPR screens and functional validation.

bioRxiv · Jun 1, 2026 · PreprintMolecular Biology

Substantial Deceleration of Adaptation of HIV-1 Within 1,500 Generations in an Experimental Evolution: A Genomic Perspective

Ali Movasati, Christine Leemann, Kathrin Neumann, Rongfeng Chen, Lygeri Sakellaridi, Karin Jutta Metzner, Roland R. Regoes

This study tracks HIV-1 adaptation over 1,500 generations in human T-cell lines, finding a substantial deceleration in adaptive mutation fixation rates and fitness gains.

Virus Evolution · Jan 1, 2026Peer-reviewedEvolutionary Biology

Pan-cancer whole genome comparison of primary and metastatic solid tumors

Francisco Martínez-Jiménez, Ali Movasati, Sascha R. Brunner, Luan Nguyen, Peter Priestley, Edwin P. J. G. Cuppen, Arne van Hoeck

This study compares whole-genome sequences of primary and metastatic tumors across 7,152 samples, revealing cancer-type-specific genomic changes and treatment-induced evolutionary bottlenecks.

bioRxiv · Jun 17, 2022 · PreprintGenomics