Molecular BiologybioRxivPreprint
Single-cell transcriptome analysis of the early immune response in the lymph nodes of Borrelia burgdorferi-infected mice
Varpu Rinne, Kirsi Gröndahl‐Yli‐Hannuksela, Ruth Fair-Mäkelä…·Jukka Hytönen
This study uses single-cell RNA sequencing to analyze the early immune response in lymph nodes of Borrelia burgdorferi-infected mice, identifying B cell proliferation, immunoglobulin class switching, and changes in gene expression associated with extrafollicular immunity.