Tapio Lönnberg

This study shows that disrupting the CIP2A gene reduces T cell-driven inflammation in experimental autoimmune encephalomyelitis.

This study identifies changes in lymphatic endothelial cell subsets and increased MGP expression in metastatic sentinel lymph nodes from breast cancer patients.

The paper identifies immune-related transcriptional changes in adipose-derived fibroblasts in obesity-associated atherosclerosis using single-cell RNA sequencing and spatial transcriptomics.

This study uses single-cell RNA sequencing to analyze the early immune response in lymph nodes of Borrelia burgdorferi-infected mice, identifying B cell proliferation, immunoglobulin class switching, and changes in gene expression associated with extrafollicular immunity.

The paper quantifies and integrates miRNA gene expression in single-cell studies, revealing age- and disease-related miRNA regulation in immune cells.

The paper identifies DNA methylation differences in peripheral blood of Alzheimer’s disease discordant twin pairs, linking these to brain gene expression and neuronal functions.

The paper uses single-cell RNA sequencing and computational modeling to resolve CD4+ T cell fate bifurcation during Plasmodium infection, showing external influence on fate decisions by monocytes.

This paper introduces TraCeR, a method to infer full-length TCR sequences from single-cell RNA-seq, revealing clonal relationships and linking them to T cell functional states in Salmonella infection.