Author

Daniel Schwabe

Max Delbrück CenterORCID 0000-0003-2825-3352Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Assay:scRNA-seq· 2 Approach:statistical model· 2 Research Focus:differential expression· 1 Organism:human· 1 Research Focus:trajectory inference· 1

Frequent Co-Authors

Martin FalckeiD· 2 shared Jan Philipp JunkeriD· 1 shared Nikolaus RajewskyiD· 1 shared Sara FormichettiiD· 1 shared

Activity by Year

2020-2021 · peak 1/yr

Co-Author Collaboration Network

4 top collaborators · 6 mutual co-author links

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2 shared papersGenomics

Martin FalckeORCID

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2 papers

Recent·Most cited

GenomicsBioinformaticsPeer-reviewedDec 12, 2021

On the relation between input and output distributions of scRNA-seq experiments

Daniel Schwabe, Martin Falcke

The paper models how technical noise in scRNA-seq affects output distributions compared to input distributions and shows the output coefficient of variation is always higher.

1 citation

humanscRNA-seq

𝕏 PostBluesky

Systems BiologyMolecular Systems BiologyPeer-reviewedNov 1, 2020

The transcriptome dynamics of single cells during the cell cycle

Daniel Schwabe, Sara Formichetti, Jan Philipp Junker…·Nikolaus Rajewsky

The paper reveals that cells move in a circular trajectory in transcriptome space during the cell cycle, minimizing transcriptional changes.

80 citations

scRNA-seqstatistical model

𝕏 PostBluesky